Int J Burn Trauma 2012;2(1):29-41
Review Article
Nanomaterials and nanotechnology for skin tissue engineering
Aezeden Mohamed, Malcolm (Mengqiu) Xing
Nano-Medicine and Tissue Engineering Lab, Department of Mechanical and Manufacturing Engineering, Faculty of
Engineering, Department of Biochemistry and Medical Genetics, Faculty of Medicine, University of Manitoba and Manitoba
Institute of Child Health, Winnipeg, Manitoba, Canada.
Received January 23, 2012; accepted February 20, 2012; Epub March 15, 2012; published March 30, 2012
Abstract: A recent literature review of the field shows that tissue-engineered skin has been in clinical use for the last several
decades and that, over this time the technology has advanced rapidly. Despite this progress no synthetic skin yet produced
has completely replicated normal, healthy skin. Therefore, researchers must continue to develop materials that successfully
overcome the problems with current skin tissue substitutes. This paper is a comprehensive review of the prospects for
nanotechnology and nanomaterials to close this gap by mimicing surface properties for reconstruction of a variety of skin
tissues. In addition, a number of commercially available products that regenerate different layers of the burn-damaged or
chronically wounded skin are reviewed. (IJBT1201002).
Keywords: Skin, regeneration, scaffold, tissue engineering
Address correspondence to:
Dr. Malcolm (Mengqiu) Xing
Manitoba Institute of Child Health
Phone: 204-474-6301 (Fort Garry), 204-480-1396 (Bannatyne)
Office: E1-573 EITC (Fort Garry), 656-A (John Buhler Research Centre, MICH)
xing@cc.umanitoba.ca
Winnipeg, Manitoba
R3T 5V6
Review Article
Nanomaterials and nanotechnology for skin tissue engineering
Aezeden Mohamed, Malcolm (Mengqiu) Xing
Nano-Medicine and Tissue Engineering Lab, Department of Mechanical and Manufacturing Engineering, Faculty of
Engineering, Department of Biochemistry and Medical Genetics, Faculty of Medicine, University of Manitoba and Manitoba
Institute of Child Health, Winnipeg, Manitoba, Canada.
Received January 23, 2012; accepted February 20, 2012; Epub March 15, 2012; published March 30, 2012
Abstract: A recent literature review of the field shows that tissue-engineered skin has been in clinical use for the last several
decades and that, over this time the technology has advanced rapidly. Despite this progress no synthetic skin yet produced
has completely replicated normal, healthy skin. Therefore, researchers must continue to develop materials that successfully
overcome the problems with current skin tissue substitutes. This paper is a comprehensive review of the prospects for
nanotechnology and nanomaterials to close this gap by mimicing surface properties for reconstruction of a variety of skin
tissues. In addition, a number of commercially available products that regenerate different layers of the burn-damaged or
chronically wounded skin are reviewed. (IJBT1201002).
Keywords: Skin, regeneration, scaffold, tissue engineering
Address correspondence to:
Dr. Malcolm (Mengqiu) Xing
Manitoba Institute of Child Health
Phone: 204-474-6301 (Fort Garry), 204-480-1396 (Bannatyne)
Office: E1-573 EITC (Fort Garry), 656-A (John Buhler Research Centre, MICH)
xing@cc.umanitoba.ca
Winnipeg, Manitoba
R3T 5V6
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